Top1 express
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Top1 express
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Web21. mar 2024 · TOP1 (DNA Topoisomerase I) is a Protein Coding gene. Diseases associated with TOP1 include Systemic Scleroderma and Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 1.Among its related pathways are Transport of the SLBP independent Mature mRNA and Metabolism of proteins.Gene Ontology (GO) annotations … Webegies. Notchpathway andDNA topoisomerase I(TOP1)inhibitorshave beenwidely usedin cisplatin-resistantovariancancers [5]. However,patientscandevelop TOP1 inhibitorresis-tance, thushampering thesuccess oftherapy [6]. Useofcombination therapy oversingle-agent chemotherapy leads toimproved outcomesinovarian cancer[7].Chemotherapy-induced side
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Web24. júl 2015 · TOP1 expres-sion was significantly higher in neoplasms than in normal tissues, as evaluated using IHC (Fig. 1B, p < 0.001). We next investigated the relationship between TOP1 expression levels and ...
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