WebThe Highest Single Agent (HSA) model, or Gaddum’s non-interaction reference (Berenbaum 1989), is based on the intuition that if a combination’s effect exceeds those of its … Web12 Apr 2024 · The HSA model, unlike the other three, is primarily used in situations where no single agent can achieve 100% response (e.g., many cancer therapeutics), where a …
SynergyFinder: a web application for analyzing drug combination …
Web18 May 2024 · Highest single-agent synergy (HSA), a model that measures synergy as net increase in sensitivity to the combination beyond the most potent single agent, was … Web1 Jan 2015 · There are three frequently-used reference models: Highest single agent (HSA), Bliss independence and Loewe additivity. The HSA model states that the expected … federal and provincial employee tax forms
Associating drug sensitivity with differentiation status identifies
WebSearch for abbreviations and long forms in lifescience, results along with the related PubMed / MEDLINE information and co-occurring abbreviations. Web19 Jan 2024 · Highest Single Agent. A null model based on the Highest Single Agent (HSA) model does not attempt to model interaction effects at all and the predicted effect of a … WebDescription. The Highest Single Agent (HSA) model, or Gaddum's non-interaction reference (Berenbaum 1989), is based on the intuition that if a combination's effect exceeds those of its constituents, there must be some interaction. Mathematically, the HSA model is a … declaring bankruptcy in north carolina