Phospho gamma h2ax
WebFeb 4, 2010 · Phosphorylation of the Ser-139 residue of the histone variant H2AX, forming γH2AX, is an early cellular response to the induction of DNA double-strand breaks. … Webgamma-H2AX Antibodies. Antibodies that detect gamma-H2AX can be used in several scientific applications, including Immunocytochemistry, Immunohistochemistry, Western Blot, Immunoprecipitation and ELISA. These antibodies target gamma-H2AX in Human, Mouse, Rat and All samples. Our gamma-H2AX polyclonal and recombinant monoclonal …
Phospho gamma h2ax
Did you know?
WebThe breast cancer cell lines SKBR3 remained unaffected whereas MCF7 did show higher DNA damage upon each treatment. Importantly, even if MCF10A showed significant H2AX … WebFeb 11, 2024 · body mass index modifies the relationship between gamma-h2ax, a dna damage biomarker, and pathological complete response in triple-negative breast can
WebAnti-phospho-Histone H2A.X (Ser139), clone JBW301 is a well published Mouse Monoclonal Antibody validated in ChIP, ICC, IF, WB. This purified mAb is highly specific for phospho-Histone H2A.X (Ser139) More>> MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References WebThe UVB lamp is also the best inducer of gamma-H2AX expression and cyclobutane pyrimidine dimers formation. However, the UVA-340 lamp is a better inducer for ATF4 expression. Our results indicate that different spectral characteristics of UV lamps can produce different results for the activation of the ER-stress responses and the differences …
WebNational Center for Biotechnology Information WebSynthetic peptide corresponding to Human gamma H2A.X (phospho S139). Synthetic peptide sequence surrounding phosphorylated Ser139 Positive control WB: Jurkat (treated with staurosporin) cell lysate. ICC: HepG2, …
WebSep 6, 2024 · p-Histone H2A.X Antibody (Ser 139) is a mouse monoclonal IgG 1, cited in 82 publications, provided at 100 µg/ml raised against a recombinant protein corresponding to the Ser 139 phosphorylated region of Histone H2A.X of human origin recommended for detection of Ser 139 phosphorylated Histone H2A.X of mouse, rat and human origin by … cheryl marraWebThe PathScan® Phospho-Histone H2A.X (Ser139) Sandwich ELISA Kit is a solid phase sandwich enzyme-linked immunosorbent assay (ELISA) that detects endogenous levels of histone H2A.X protein phosphorylated at Ser139. A histone H2A.X rabbit antibody has been coated onto the microwells. flights to mariscal beachWebPhospho-H2A.X (Ser139) Antibody detects endogenous levels of H2A.X only when phosphorylated at Ser139. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Antibodies are produced by immunizing … cherylmarrie-beautyWebAnti-gamma H2A.X (phospho S139) antibody [9F3] See all gamma H2A.X primary antibodies Description Mouse monoclonal [9F3] to gamma H2A.X (phospho S139) Host species Mouse Tested applications Suitable for: … flights to marksuhlWebGamma-H2AX is a sensitive target for looking at DSBs in cells. Dephosphorylation of Ser-140 by PP2A is required for DNA DSB repair. The role of the phosphorylated form of the histone in DNA repair is under. Anti-H2AX pS139 is ideal for researched interested in Histones, DNA Damage and Repair, and Epigenetics. Application Note cherylmarriaWebHistone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs. flights to marion reservoirWebH2A.X becomes phosphorylated on serine 139 after double-stranded DNA breaks. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. The 2F3 monoclonal antibody reacts with phosphorylated human H2A.X (Ser139) and has been shown to be useful for Western blotting, immunofluorescence and flow cytometry. … cheryl marriage