Web30 jul. 2024 · Estimated effect of statin discontinuation in patient subgroups. a Low intensity: fluvastatin 20–40 mg, pravastatin 10–20 mg, simvastatin 5–10 mg; moderate intensity: atorvastatin 10–20 mg, rosuvastatin 5–10 mg, fluvastatin 80 mg, pravastatin 40 mg, simvastatin 20–40 mg; high intensity: atorvastatin 40–80 mg, rosuvastatin 20 mg … Web3 apr. 2024 · Conclusions and relevance: Among patients with acute myocardial infarction, the addition of subcutaneous biweekly alirocumab, compared with placebo, to high-intensity statin therapy resulted...
STK-6 (v2024A1) - Performance Measurement Network
Web17 sep. 2024 · In this setting, the combination of ezetimibe and a moderate-intensity statin could be an alternative strategy to high-intensity statins in secondary prevention. Ezetimibe inhibits absorption of cholesterol from the gastrointestinal tract and lowers LDL-C levels by 15–22% with low incidence of side effects and without increasing the risk of … Web3 aug. 2024 · In this study, a moderate-intensity statin plus ezetimibe was noninferior to a high-intensity statin for cardiovascular outcomes in patients with ASCVD. Further, the combination therapy achieved more LDL reduction … pain in my right thigh muscle
Statin Therapy for the Prevention and Treatment of Cardiovascular ...
Web4 sep. 2015 · The intensity of a statin is defined based on the percentage reduction in low‑density lipoprotein (LDL) cholesterol it can produce. A high‑intensity statin can produce a reduction above 40%. High‑intensity statins include: atorvastatin 20 mg to 80 mg rosuvastatin 10 mg to 40 mg simvastatin 80 mg. [ NICE's guideline on cardiovascular … Web9 feb. 2024 · Management: Limit atorvastatin to a maximum adult dose of 20 mg/day in patients receiving itraconazole. Assess clinical response to ensure that the lowest necessary dose of atorvastatin is used. Consider use of fluva-, rosuva-, pitava-, or pravastatin when possible. Consider therapy modification. Web23 aug. 2024 · Background Whether high-intensity statin treatment provides more clinical benefits compared with standard statin regimens in acute coronary syndrome (ACS) patients remains controversial. This meta-analysis aimed to comparatively assess high-intensity and standard statin regimens for efficacy and safety in patients with ACS. … subform in sharepoint