Dynamo mapping vector field of single cells
WebFeb 1, 2024 · The researchers confirmed dynamo 's cell fate predictions by testing it against cloned cells-cells that share the same genetics and ancestry. One of two nearly-identical clones would be sequenced ... WebSingle-cell RNA-seq pseudotime estimation algorithms. Single cells, many algorithms. The goal of this page is to catalog the many algorithms that estimate pseudotimes for cells based on their gene expression levels. This problem is also referred to as single-cell trajectory inference or ordering.
Dynamo mapping vector field of single cells
Did you know?
WebQiu X, Zhang Y, Yang D, et al. Mapping vector field of single cells[J]. Biorxiv, 2024. 这个 RNA velocity and beyond 系列之后大概会写 Theory 部分 ，主要介绍 model detail，怎么 estimate parameter等，最后写 beyond 的部分，也就是dynamo 的内容。 欢迎大家在评论区讨论（虽然我估计没什么人看hhhh） WebFeb 17, 2024 · In this work, we introduced dynamical systems theory and differential geometry analyses to single-cell genomics. A dynamical system describes the time …
WebFeb 18, 2024 · To enable such temporal analysis from multimodal single-cell experiments, we introduce an extension of the RNA velocity method that leverages estimates of unprocessed transcript and protein abundances to extrapolate cell states. ... Wang L, Yuan R, et al. Mapping Vector Field of Single Cells. Biorxiv. 2024;9:696724. Google Scholar … WebJul 9, 2024 · Abstract. Single-cell RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however ...
WebFeb 1, 2024 · Dynamo is a computational framework for gaining insights into dynamic biological processes, such as human hematopoiesis, from time-resolved single-cell RNA-seq data. Dynamo constructs … WebLeveraging the least-action-path method, dynamo accurately predicts drivers of numerous hematopoietic transitions. Finally, in silico perturbations predict cell-fate diversions induced by gene perturbations. Dynamo, thus, represents an important step in advancing quantitative and predictive theories of cell-state transitions.
Web•Vector fields reveal the timing and mechanisms of human hematopoiesis •Dynamo allows cell-state transition path and in silico perturbation predictions . Summary. Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution.
WebFeb 17, 2024 · Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting … phils brotherWebDynamo: Mapping Vector Field of Single Cells¶ Understanding how gene expression in single cells progress over time is vital for revealing the mechanisms governing cell fate … t shirts that hide tummyhttp://dynamo-readthedocs.readthedocs.io/ phils bongo room avalonWebLeveraging the least-action-path method, dynamo accurately predicts drivers of numerous hematopoietic transitions. Finally, in silico perturbations predict cell-fate diversions … phils brewers game toniteWebFeb 9, 2024 · Here, we introduce dynamo, an analytical framework that reconciles intrinsic splicing and labeling kinetics to estimate absolute RNA velocities, reconstructs velocity … phils body shop copperas coveWebDynamo. : Mapping Vector Field of Single Cells. Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these … philsca admission log inWebJul 9, 2024 · Here, we introduce dynamo , an analytical framework that reconciles intrinsic splicing and labeling kinetics to estimate absolute RNA velocities, reconstructs velocity vector fields that predict future cell fates, and finally employs differential geometry analyses to elucidate the underlying regulatory networks. philsca admission office